藥物交互作用
Insulin degludec + Insulin glargine-lixisenatide
嚴重程度: 嚴重
Insulin degludec and Insulin glargine-lixisenatide: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
This combination product already contains basal insulin, so adding insulin degludec duplicates basal insulin therapy. The result is a high risk of hypoglycemia from overlapping basal coverage.
用白話說明這項交互作用的意義
Insulin degludec and Insulin glargine-lixisenatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin degludec belongs to Endocrine; Insulin glargine-lixisenatide belongs to Endocrine.
為什麼會發生
Therapeutic duplication with additive insulin effect.
處置方式
Avoid using two basal insulins together; use one regimen and adjust doses to the patient's glycemic needs. If switching, stop the other basal insulin and monitor glucose closely.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Insulin glargine-lixisenatide 的其他交互作用
Insulin degludec 的其他交互作用
常見問題
Can I take Insulin degludec with Insulin glargine-lixisenatide?
MediHelp rates the interaction as major. Insulin degludec and Insulin glargine-lixisenatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. This combination product already contains basal insulin, so adding insulin degludec duplicates basal insulin therapy. The result is a high risk of hypoglycemia from overlapping basal coverage.
How serious is the interaction between Insulin degludec and Insulin glargine-lixisenatide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using two basal insulins together; use one regimen and adjust doses to the patient's glycemic needs. If switching, stop the other basal insulin and monitor glucose closely.
What other medicines interact with Insulin glargine-lixisenatide?
MediHelp also lists interactions of Insulin glargine-lixisenatide with, for example, Albiglutide, Chlorpropamide, Dulaglutide. The full list is on the Insulin glargine-lixisenatide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
