藥物交互作用
Dulaglutide + Insulin glargine-lixisenatide
嚴重程度: 嚴重
Dulaglutide and Insulin glargine-lixisenatide: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Dulaglutide is a GLP-1 receptor agonist, so combining it with a product that already contains lixisenatide duplicates therapy. It gives no added benefit and increases gastrointestinal adverse effects and hypoglycemia risk.
用白話說明這項交互作用的意義
Dulaglutide and Insulin glargine-lixisenatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Dulaglutide belongs to Endocrine; Insulin glargine-lixisenatide belongs to Endocrine.
為什麼會發生
Therapeutic duplication of GLP-1 receptor agonism with additive glucose lowering.
處置方式
Avoid using two GLP-1 receptor agonists together; use only one agent.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Insulin glargine-lixisenatide 的其他交互作用
Dulaglutide 的其他交互作用
常見問題
Can I take Dulaglutide with Insulin glargine-lixisenatide?
MediHelp rates the interaction as major. Dulaglutide and Insulin glargine-lixisenatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dulaglutide is a GLP-1 receptor agonist, so combining it with a product that already contains lixisenatide duplicates therapy. It gives no added benefit and increases gastrointestinal adverse effects and hypoglycemia risk.
How serious is the interaction between Dulaglutide and Insulin glargine-lixisenatide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using two GLP-1 receptor agonists together; use only one agent.
What other medicines interact with Insulin glargine-lixisenatide?
MediHelp also lists interactions of Insulin glargine-lixisenatide with, for example, Albiglutide, Chlorpropamide, Ethanol. The full list is on the Insulin glargine-lixisenatide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
