藥物交互作用
Insulin detemir + Pentamidine
嚴重程度: 嚴重
Insulin detemir and Pentamidine: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Pentamidine can damage pancreatic beta cells, causing early hypoglycemia from insulin release and later hyperglycemia or diabetes. This makes glucose control on insulin unpredictable.
用白話說明這項交互作用的意義
Insulin detemir and Pentamidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin detemir belongs to Endocrine; Pentamidine belongs to Anti Parasitic.
為什麼會發生
Pentamidine is toxic to pancreatic beta cells, causing biphasic insulin release then deficiency.
處置方式
Monitor glucose frequently during and after pentamidine therapy. Adjust insulin detemir promptly and be ready to treat hypoglycemia.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Insulin detemir 的其他交互作用
Pentamidine 的其他交互作用
常見問題
Can I take Insulin detemir with Pentamidine?
MediHelp rates the interaction as major. Insulin detemir and Pentamidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Pentamidine can damage pancreatic beta cells, causing early hypoglycemia from insulin release and later hyperglycemia or diabetes. This makes glucose control on insulin unpredictable.
How serious is the interaction between Insulin detemir and Pentamidine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose frequently during and after pentamidine therapy. Adjust insulin detemir promptly and be ready to treat hypoglycemia.
What other medicines interact with Insulin detemir?
MediHelp also lists interactions of Insulin detemir with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin detemir page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
