藥物交互作用
Iodinated glycerol + Propylthiouracil
嚴重程度: 中度
Iodinated glycerol and Propylthiouracil: moderate interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Iodinated glycerol is an iodine-containing expectorant that delivers iodide systemically. Iodide can alter thyroid function and may add to or interfere with antithyroid therapy, with possible goiter or hypothyroidism.
用白話說明這項交互作用的意義
Iodinated glycerol and Propylthiouracil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Iodide load affects thyroid hormone synthesis and release, producing additive thyroid suppression.
處置方式
Avoid iodine-containing expectorants where possible, and monitor TSH and free T4 if they are used.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Propylthiouracil 的其他交互作用
常見問題
Can I take Iodinated glycerol with Propylthiouracil?
MediHelp rates the interaction as moderate. Iodinated glycerol and Propylthiouracil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iodinated glycerol is an iodine-containing expectorant that delivers iodide systemically. Iodide can alter thyroid function and may add to or interfere with antithyroid therapy, with possible goiter or hypothyroidism.
How serious is the interaction between Iodinated glycerol and Propylthiouracil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid iodine-containing expectorants where possible, and monitor TSH and free T4 if they are used.
What other medicines interact with Propylthiouracil?
MediHelp also lists interactions of Propylthiouracil with, for example, Carbamazepine, Clozapine, Methimazole. The full list is on the Propylthiouracil page.
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