藥物交互作用
Leflunomide + Measles mumps rubella and varicella vaccine live
嚴重程度: 禁忌併用
Leflunomide and Measles mumps rubella and varicella vaccine live: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
This live attenuated combination vaccine may cause disseminated vaccine-strain infection, including varicella, in a patient immunosuppressed by leflunomide. The immune response may also be reduced.
用白話說明這項交互作用的意義
Leflunomide and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Impaired lymphocyte function reduces control of live attenuated virus replication.
處置方式
Avoid during leflunomide therapy and until washout is confirmed; vaccinate before treatment starts.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Leflunomide 的其他交互作用
常見問題
Can I take Leflunomide with Measles mumps rubella and varicella vaccine live?
MediHelp rates the interaction as contraindicated. Leflunomide and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live attenuated combination vaccine may cause disseminated vaccine-strain infection, including varicella, in a patient immunosuppressed by leflunomide. The immune response may also be reduced.
How serious is the interaction between Leflunomide and Measles mumps rubella and varicella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during leflunomide therapy and until washout is confirmed; vaccinate before treatment starts.
What other medicines interact with Leflunomide?
MediHelp also lists interactions of Leflunomide with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Leflunomide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
