藥物交互作用
Lincomycin + Rapacuronium
嚴重程度: 嚴重
Lincomycin and Rapacuronium: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Lincosamide antibiotics have intrinsic neuromuscular blocking activity and can potentiate non-depolarizing blockers. This may prolong paralysis and delay recovery of respiratory function.
用白話說明這項交互作用的意義
Lincomycin and Rapacuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive neuromuscular blockade through presynaptic and postsynaptic effects of lincomycin.
處置方式
Monitor neuromuscular function with a nerve stimulator and maintain ventilatory support until full recovery. Reduce the neuromuscular blocker dose if needed.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Lincomycin 的其他交互作用
常見問題
Can I take Lincomycin with Rapacuronium?
MediHelp rates the interaction as major. Lincomycin and Rapacuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Lincosamide antibiotics have intrinsic neuromuscular blocking activity and can potentiate non-depolarizing blockers. This may prolong paralysis and delay recovery of respiratory function.
How serious is the interaction between Lincomycin and Rapacuronium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor neuromuscular function with a nerve stimulator and maintain ventilatory support until full recovery. Reduce the neuromuscular blocker dose if needed.
What other medicines interact with Lincomycin?
MediHelp also lists interactions of Lincomycin with, for example, Atracurium, Cisatracurium, Pancuronium. The full list is on the Lincomycin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
