藥物交互作用
Cisatracurium + Lincomycin
嚴重程度: 嚴重
Cisatracurium and Lincomycin: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Lincomycin has neuromuscular blocking activity and can potentiate non-depolarizing relaxants such as cisatracurium. This can prolong paralysis and delay return of spontaneous ventilation.
用白話說明這項交互作用的意義
Cisatracurium and Lincomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cisatracurium belongs to Musculoskeletal; Lincomycin belongs to Anti Bacterial.
為什麼會發生
Additive neuromuscular blockade via presynaptic and postsynaptic inhibition of transmission by lincomycin.
處置方式
Monitor train-of-four and titrate cisatracurium cautiously. Keep ventilatory support available until full recovery of neuromuscular function.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Cisatracurium 的其他交互作用
Lincomycin 的其他交互作用
常見問題
Can I take Cisatracurium with Lincomycin?
MediHelp rates the interaction as major. Cisatracurium and Lincomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Lincomycin has neuromuscular blocking activity and can potentiate non-depolarizing relaxants such as cisatracurium. This can prolong paralysis and delay return of spontaneous ventilation.
How serious is the interaction between Cisatracurium and Lincomycin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor train-of-four and titrate cisatracurium cautiously. Keep ventilatory support available until full recovery of neuromuscular function.
What other medicines interact with Cisatracurium?
MediHelp also lists interactions of Cisatracurium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Benzhydrocodone / acetaminophen. The full list is on the Cisatracurium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
