藥物交互作用
Lincomycin + Vecuronium
嚴重程度: 嚴重
Lincomycin and Vecuronium: major interaction.
最後更新
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摘要
Lincosamides can potentiate non-depolarising muscle relaxants and prolong neuromuscular blockade. Reports describe delayed recovery and respiratory depression after combined use.
用白話說明這項交互作用的意義
Lincomycin and Vecuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Lincomycin belongs to Anti Bacterial; Vecuronium belongs to Musculoskeletal.
為什麼會發生
Lincomycin has weak intrinsic neuromuscular blocking activity acting at pre- and postsynaptic sites, adding to vecuronium's effect.
處置方式
Monitor neuromuscular function with a train-of-four monitor and titrate vecuronium to effect. Ensure ventilatory support until recovery is complete, or choose a different antibiotic.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Vecuronium 的其他交互作用
Lincomycin 的其他交互作用
常見問題
Can I take Lincomycin with Vecuronium?
MediHelp rates the interaction as major. Lincomycin and Vecuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Lincosamides can potentiate non-depolarising muscle relaxants and prolong neuromuscular blockade. Reports describe delayed recovery and respiratory depression after combined use.
How serious is the interaction between Lincomycin and Vecuronium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor neuromuscular function with a train-of-four monitor and titrate vecuronium to effect. Ensure ventilatory support until recovery is complete, or choose a different antibiotic.
What other medicines interact with Vecuronium?
MediHelp also lists interactions of Vecuronium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Vecuronium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
