藥物交互作用
Maribavir + Phenytoin
嚴重程度: 中度
Maribavir and Phenytoin: moderate interaction.
最後更新
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摘要
Phenytoin lowers maribavir concentrations and may compromise control of CMV infection.
用白話說明這項交互作用的意義
Maribavir and Phenytoin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Maribavir belongs to Anti Virals; Phenytoin belongs to Central Nervous System.
為什麼會發生
Phenytoin induces CYP3A4, increasing maribavir metabolism.
處置方式
If coadministration is needed, increase the maribavir dose as directed by labeling and monitor CMV viral load. Consider a non-inducing anticonvulsant where possible.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Maribavir 的其他交互作用
Phenytoin 的其他交互作用
常見問題
Can I take Maribavir with Phenytoin?
MediHelp rates the interaction as moderate. Maribavir and Phenytoin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Phenytoin lowers maribavir concentrations and may compromise control of CMV infection.
How serious is the interaction between Maribavir and Phenytoin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: If coadministration is needed, increase the maribavir dose as directed by labeling and monitor CMV viral load. Consider a non-inducing anticonvulsant where possible.
What other medicines interact with Maribavir?
MediHelp also lists interactions of Maribavir with, for example, Ganciclovir, Rifampicin, Valganciclovir. The full list is on the Maribavir page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
