藥物交互作用
Maribavir + Valganciclovir
嚴重程度: 嚴重
Maribavir and Valganciclovir: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Maribavir may reduce the antiviral activity of valganciclovir, the prodrug of ganciclovir, against cytomegalovirus. This could lead to treatment failure.
用白話說明這項交互作用的意義
Maribavir and Valganciclovir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Maribavir belongs to Anti Virals; Valganciclovir belongs to Anti Virals.
為什麼會發生
Maribavir inhibits the viral UL97 kinase, which is needed to phosphorylate ganciclovir to its active form.
處置方式
Do not coadminister; choose one agent according to the treatment plan. Monitor CMV viral load if switching therapies.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Maribavir 的其他交互作用
Valganciclovir 的其他交互作用
常見問題
Can I take Maribavir with Valganciclovir?
MediHelp rates the interaction as major. Maribavir and Valganciclovir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Maribavir may reduce the antiviral activity of valganciclovir, the prodrug of ganciclovir, against cytomegalovirus. This could lead to treatment failure.
How serious is the interaction between Maribavir and Valganciclovir?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not coadminister; choose one agent according to the treatment plan. Monitor CMV viral load if switching therapies.
What other medicines interact with Maribavir?
MediHelp also lists interactions of Maribavir with, for example, Ganciclovir, Rifampicin, Carbamazepine. The full list is on the Maribavir page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
