藥物交互作用
Ganciclovir + Valganciclovir
嚴重程度: 嚴重
Ganciclovir and Valganciclovir: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Valganciclovir is the oral prodrug of ganciclovir, so the two are the same active substance and combining them duplicates therapy. This raises exposure and the risk of hematologic and other dose-related toxicity.
用白話說明這項交互作用的意義
Ganciclovir and Valganciclovir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ganciclovir belongs to Anti Virals; Valganciclovir belongs to Anti Virals.
為什麼會發生
Therapeutic duplication, since valganciclovir is converted to ganciclovir.
處置方式
Avoid concurrent use; give only one agent, switching from intravenous ganciclovir to oral valganciclovir when appropriate. Monitor blood counts if an overlap occurs.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Ganciclovir 的其他交互作用
Valganciclovir 的其他交互作用
常見問題
Can I take Ganciclovir with Valganciclovir?
MediHelp rates the interaction as major. Ganciclovir and Valganciclovir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Valganciclovir is the oral prodrug of ganciclovir, so the two are the same active substance and combining them duplicates therapy. This raises exposure and the risk of hematologic and other dose-related toxicity.
How serious is the interaction between Ganciclovir and Valganciclovir?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use; give only one agent, switching from intravenous ganciclovir to oral valganciclovir when appropriate. Monitor blood counts if an overlap occurs.
What other medicines interact with Ganciclovir?
MediHelp also lists interactions of Ganciclovir with, for example, Bacitracin, Cilastatin-imipenem, Didanosine. The full list is on the Ganciclovir page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
