藥物交互作用
Measles mumps and rubella vaccine + Sirolimus
嚴重程度: 禁忌併用
Measles mumps and rubella vaccine and Sirolimus: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Sirolimus is a potent immunosuppressant used in transplantation. It may reduce vaccine response and allow the live vaccine viruses to replicate, raising the risk of vaccine-strain infection.
用白話說明這項交互作用的意義
Measles mumps and rubella vaccine and Sirolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Measles mumps and rubella vaccine belongs to Miscellaneous; Sirolimus belongs to Miscellaneous.
為什麼會發生
mTOR inhibition suppresses T-cell proliferation, impairing control of live attenuated virus.
處置方式
Avoid live vaccines during sirolimus therapy. Give MMR before transplant or immunosuppression where possible.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Measles mumps and rubella vaccine 的其他交互作用
- Adalimumab + Measles mumps and rubella vaccine 禁忌併用
- Anakinra + Measles mumps and rubella vaccine 禁忌併用
- Antithymocyte globulin equine + Measles mumps and rubella vaccine 禁忌併用
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine 禁忌併用
- Azathioprine + Measles mumps and rubella vaccine 禁忌併用
- Basiliximab + Measles mumps and rubella vaccine 禁忌併用
Sirolimus 的其他交互作用
常見問題
Can I take Measles mumps and rubella vaccine with Sirolimus?
MediHelp rates the interaction as contraindicated. Measles mumps and rubella vaccine and Sirolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Sirolimus is a potent immunosuppressant used in transplantation. It may reduce vaccine response and allow the live vaccine viruses to replicate, raising the risk of vaccine-strain infection.
How serious is the interaction between Measles mumps and rubella vaccine and Sirolimus?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during sirolimus therapy. Give MMR before transplant or immunosuppression where possible.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
