藥物交互作用
Bcg vaccine live + Sirolimus
嚴重程度: 禁忌併用
Bcg vaccine live and Sirolimus: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Sirolimus suppresses immune responses, so a live BCG vaccine may fail to produce protection and may cause disseminated BCG infection. Live vaccines are generally avoided in patients on immunosuppressive therapy.
用白話說明這項交互作用的意義
Bcg vaccine live and Sirolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Sirolimus-mediated immunosuppression allows uncontrolled replication of the live attenuated organism and blunts the vaccine response.
處置方式
Do not give live BCG vaccine during sirolimus therapy. Vaccinate before starting immunosuppression where feasible.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Sirolimus 的其他交互作用
常見問題
Can I take Bcg vaccine live with Sirolimus?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Sirolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Sirolimus suppresses immune responses, so a live BCG vaccine may fail to produce protection and may cause disseminated BCG infection. Live vaccines are generally avoided in patients on immunosuppressive therapy.
How serious is the interaction between Bcg vaccine live and Sirolimus?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live BCG vaccine during sirolimus therapy. Vaccinate before starting immunosuppression where feasible.
What other medicines interact with Sirolimus?
MediHelp also lists interactions of Sirolimus with, for example, Adenovirus types 4 and 7 live, Influenza virus vaccine quadrivalent intranasal, Ketoconazole. The full list is on the Sirolimus page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
