藥物交互作用
Mestranol + Tranexamic acid
嚴重程度: 禁忌併用
Mestranol and Tranexamic acid: contraindicated interaction.
最後更新
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摘要
Oral tranexamic acid is antifibrinolytic and mestranol, a prodrug of ethinylestradiol, is prothrombotic. Together they raise the risk of venous and arterial thrombosis, and oral tranexamic acid labeling contraindicates use with combined hormonal contraceptives.
用白話說明這項交互作用的意義
Mestranol and Tranexamic acid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Additive prothrombotic effects of fibrinolysis inhibition and estrogen-induced increases in clotting factors.
處置方式
Avoid the combination; use non-hormonal or progestin-only contraception while taking tranexamic acid, or choose another heavy-bleeding treatment.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Tranexamic acid 的其他交互作用
常見問題
Can I take Mestranol with Tranexamic acid?
MediHelp rates the interaction as contraindicated. Mestranol and Tranexamic acid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Oral tranexamic acid is antifibrinolytic and mestranol, a prodrug of ethinylestradiol, is prothrombotic. Together they raise the risk of venous and arterial thrombosis, and oral tranexamic acid labeling contraindicates use with combined hormonal contraceptives.
How serious is the interaction between Mestranol and Tranexamic acid?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination; use non-hormonal or progestin-only contraception while taking tranexamic acid, or choose another heavy-bleeding treatment.
What other medicines interact with Tranexamic acid?
MediHelp also lists interactions of Tranexamic acid with, for example, Dienogest / estradiol valerate, Ethinyl estradiol-drospirenone, Ethinyl estradiol-levonorgestrel. The full list is on the Tranexamic acid page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
