藥品參考
Tranexamic acid
Tranexamic acid is a medicine in the class cardiovascular. It is used for hemorrhage.
- 藥物類別: Cardiovascular
- 用途: hemorrhage
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Cardiovascular
- 常見劑型
- 注射劑, 錠劑
- 常見規格
- 500 mg, 500 mg/5 ml, 100 mg/ml
- 已知交互作用
- 16 (禁忌併用: 6 · 嚴重: 7 · 中度: 3)
- 商品名
- 37
- 國家與市場
- 4
用途
作用方式
Antifibrinolytic; synthetic lysine amino acid derivative, which diminishes the dissolution of hemostatic fibrin by plasmin In the presence of tranexamic acid, the lysine receptor binding sites of plasmin for fibrin are occupied, preventing binding to fibrin monomers, thus preserving and stabilizing fibrin’s matrix structure
成人常用劑量（仿單摘要）
Menorrhagia: 1300 mg PO TID for up to 5 days during menstruation
懷孕與哺乳
- 懷孕
- Safe Crosses the placenta. Use in the 2nd and 3rd trimesters and at delivery has not shown clear harm, and it is widely used for bleeding after birth (WHO). Rare fatal fetal abnormalities after 1st-trimester use, with confounders. No harm in animals. Use when needed for bleeding, not for heavy periods.
- 哺乳
- Safe Passes into milk in low amounts. US/UK labels: no final assessment; weigh benefits. LactMed: expert opinion considers that breastfeeding should be permitted when the mother needs tranexamic acid.
已通報的副作用
- Headache
- Nausea
- Back pain
- Nasal and sinus symptoms
- Visual abnormalities
哪些人需要特別留意
- May cause cerebral edema and cerebral infarction in women with subarachnoid hemorrhage
- Severe allergic reaction reported; anaphylactic shock reported with IV product
- Concurrent use with tretinoin may exacerbate procoagulant effects
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (16)
- Dienogest / estradiol valerate + Tranexamic acid Contraindicated
- Ethinyl estradiol-drospirenone + Tranexamic acid Contraindicated
- Ethinyl estradiol-levonorgestrel + Tranexamic acid Contraindicated
- Ethinyl estradiol-norgestimate + Tranexamic acid Contraindicated
- Ethinylestradiol + Tranexamic acid Contraindicated
- Mestranol + Tranexamic acid Contraindicated
- Alteplase + Tranexamic acid Major
- Anti-inhibitor coagulant complex + Tranexamic acid Major
- Factor ix + Tranexamic acid Major
- Factor ix complex + Tranexamic acid Major
同類別的其他藥品
常見問題
What is Tranexamic acid used for?
Tranexamic acid is a medicine in the class cardiovascular. It is used for Hemorrhage, Melasma, Menorrhagia, Uterine fibroids.
What side effects have been reported with Tranexamic acid?
Headache, Nausea, Back pain, Nasal and sinus symptoms, Visual abnormalities.
Can Tranexamic acid be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Crosses the placenta. Use in the 2nd and 3rd trimesters and at delivery has not shown clear harm, and it is widely used for bleeding after birth (WHO). Rare fatal fetal abnormalities after 1st-trimester use, with confounders. No harm in animals. Use when needed for bleeding, not for heavy periods. Breastfeeding: Safe. Passes into milk in low amounts. US/UK labels: no final assessment; weigh benefits. LactMed: expert opinion considers that breastfeeding should be permitted when the mother needs tranexamic acid.
What does Tranexamic acid interact with?
MediHelp lists 16 known interactions for Tranexamic acid. Contraindicated: 6 · Major: 7 · Moderate: 3. The most serious include Dienogest / estradiol valerate, Ethinyl estradiol-drospirenone, Ethinyl estradiol-levonorgestrel.
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