藥物交互作用
Mifepristone + Prednisolone
嚴重程度: 禁忌併用
Mifepristone and Prednisolone: contraindicated interaction.
最後更新
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摘要
Mifepristone antagonizes glucocorticoid receptors and can reduce the effect of corticosteroids. In patients on long-term steroid treatment this may cause adrenal insufficiency or loss of disease control, and labeling lists chronic corticosteroid therapy as a contraindication.
用白話說明這項交互作用的意義
Mifepristone and Prednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Mifepristone belongs to Endocrine; Prednisolone belongs to Endocrine.
為什麼會發生
Mifepristone blocks glucocorticoid receptors, opposing the effect of prednisolone.
處置方式
Do not use mifepristone in patients on long-term corticosteroid therapy. Seek specialist advice if both are needed, as standard steroid doses may be ineffective.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Prednisolone 的其他交互作用
Mifepristone 的其他交互作用
常見問題
Can I take Mifepristone with Prednisolone?
MediHelp rates the interaction as contraindicated. Mifepristone and Prednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Mifepristone antagonizes glucocorticoid receptors and can reduce the effect of corticosteroids. In patients on long-term steroid treatment this may cause adrenal insufficiency or loss of disease control, and labeling lists chronic corticosteroid therapy as a contraindication.
How serious is the interaction between Mifepristone and Prednisolone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use mifepristone in patients on long-term corticosteroid therapy. Seek specialist advice if both are needed, as standard steroid doses may be ineffective.
What other medicines interact with Prednisolone?
MediHelp also lists interactions of Prednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Prednisolone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
