藥物交互作用
Phenytoin + Tiratricol
嚴重程度: 中度
Phenytoin and Tiratricol: moderate interaction.
最後更新
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摘要
Phenytoin induces hepatic enzymes and can accelerate the clearance of thyroid hormones and analogues. Tiratricol effect may be reduced.
用白話說明這項交互作用的意義
Phenytoin and Tiratricol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Phenytoin belongs to Central Nervous System; Tiratricol belongs to Endocrine.
為什麼會發生
Hepatic enzyme induction (including glucuronidation) by phenytoin increases tiratricol clearance.
處置方式
Monitor T3 and clinical thyroid status, and raise the tiratricol dose if needed. Reassess when phenytoin is changed or stopped.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Tiratricol 的其他交互作用
Phenytoin 的其他交互作用
常見問題
Can I take Phenytoin with Tiratricol?
MediHelp rates the interaction as moderate. Phenytoin and Tiratricol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Phenytoin induces hepatic enzymes and can accelerate the clearance of thyroid hormones and analogues. Tiratricol effect may be reduced.
How serious is the interaction between Phenytoin and Tiratricol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor T3 and clinical thyroid status, and raise the tiratricol dose if needed. Reassess when phenytoin is changed or stopped.
What other medicines interact with Tiratricol?
MediHelp also lists interactions of Tiratricol with, for example, Levothyroxine, Calcium, Carbamazepine. The full list is on the Tiratricol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。