Drug reference
carfilzomib
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Oncology (Anti Neoplastics)
Mechanism of action
Tetrapeptide epoxyketone proteasome inhibitor that irreversibly binds to the N-terminal threonine-containing active sites of the 20S proteasome, the proteolytic core particle within the 26S proteasome; has antiproliferative and proapoptotic activities in vitro in solid and hematologic tumor cells
Common side effects
- Anemia
- Fatigue
- Nausea
- Dyspnea
- Thrombocytopenia
- Pyrexia
- Diarrhea
Related conditions
Frequently asked questions
What drug class is carfilzomib?
carfilzomib belongs to: Oncology.
How does carfilzomib work?
Tetrapeptide epoxyketone proteasome inhibitor that irreversibly binds to the N-terminal threonine-containing active sites of the 20S proteasome, the proteolytic core particle within the 26S proteasome; has antiproliferative and proapoptotic activities in vitro in solid and hematologic tumor cells
What are the common side effects of carfilzomib?
Anemia, Fatigue, Nausea, Dyspnea, Thrombocytopenia, Pyrexia, Diarrhea
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