Drug reference
cilastatin-imipenem
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Bacterial (Carbapenems)
Mechanism of action
Imipenem inhibits bacterial cell-wall synthesis by binding to penicillin-binding proteins; cilastatin prevents renal metabolism of imipenem.
Common side effects
- Phlebitis
- Eosinophilia
- Miscellaneous dermatologic effects
- Potentially false-positive Coombs test
- Miscellaneous hematologic effects
Related conditions
Frequently asked questions
What drug class is cilastatin-imipenem?
cilastatin-imipenem belongs to: Anti Bacterial.
How does cilastatin-imipenem work?
Imipenem inhibits bacterial cell-wall synthesis by binding to penicillin-binding proteins; cilastatin prevents renal metabolism of imipenem.
What are the common side effects of cilastatin-imipenem?
Phlebitis, Eosinophilia, Miscellaneous dermatologic effects, Potentially false-positive Coombs test, Miscellaneous hematologic effects
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