Drug reference

desipramine

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Central Nervous System (Tricyclic Antidepressants)

Mechanism of action

Neurotransmitter (esp NE & serotonin) reuptake inhibitor; inhibits reuptake by neuronal membrane; may also downregulate beta-adrenergic receptors and serotonin receptors

Common side effects

  • Dry mouth
  • Constipation
  • Sedation
  • Blurred vision
  • Fatigue
  • Lethargy
  • Weakness

Related conditions

Frequently asked questions

What drug class is desipramine?

desipramine belongs to: Central Nervous System.

How does desipramine work?

Neurotransmitter (esp NE & serotonin) reuptake inhibitor; inhibits reuptake by neuronal membrane; may also downregulate beta-adrenergic receptors and serotonin receptors

What are the common side effects of desipramine?

Dry mouth, Constipation, Sedation, Blurred vision, Fatigue, Lethargy, Weakness

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