Drug reference

dexmedetomidine

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Central Nervous System (Anesthetics)

Mechanism of action

Centrally acting alpha2-adrenoceptor agonist, Elicits sedative and anesthetic properties by activating G-proteins in the brainstem, which results in inhibition of norepinephrine release

Common side effects

  • Nausea
  • Bradycardia
  • Hypotension
  • Pyrexia
  • Hypertension

Related conditions

Frequently asked questions

What drug class is dexmedetomidine?

dexmedetomidine belongs to: Central Nervous System.

How does dexmedetomidine work?

Centrally acting alpha2-adrenoceptor agonist, Elicits sedative and anesthetic properties by activating G-proteins in the brainstem, which results in inhibition of norepinephrine release

What are the common side effects of dexmedetomidine?

Nausea, Bradycardia, Hypotension, Pyrexia, Hypertension

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug reference