Drug reference
liposomal doxorubicin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Oncology (Cytotoxic Antibiotics)
Mechanism of action
Anthracycline; intercalates between DNA base pairs, impairs topoisomerase II function and subsequently inhibits DNA and RNA replication. Doxorubicin is a strong chelator; doxorubicin-iron complex binds to cell membranes and DNA and produces free hydroxyl radicals that cleaves them.
Common side effects
- Asthenia
- Neutropenia
- Anemia
- Nausea
- Thrombocytopenia
- Stomatitis
Related conditions
Frequently asked questions
What drug class is liposomal doxorubicin?
liposomal doxorubicin belongs to: Oncology.
How does liposomal doxorubicin work?
Anthracycline; intercalates between DNA base pairs, impairs topoisomerase II function and subsequently inhibits DNA and RNA replication. Doxorubicin is a strong chelator; doxorubicin-iron complex binds to cell membranes and DNA and produces free hydroxyl radicals that cleaves them.
What are the common side effects of liposomal doxorubicin?
Asthenia, Neutropenia, Anemia, Nausea, Thrombocytopenia, Stomatitis
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