Drug reference
melphalan
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Oncology (Alkylating Agents)
Mechanism of action
Mechorethamine derivative that inhibits DNA & RNA synthesis via formation of carbonium ions; cross links DNA strands (interstrand and intrastrand crosslinking) causing miscoding breakage and subsequently DNA replication failure
Common side effects
- Vomiting
- Nausea
- Myelosuppression
- Stomatitis
- Interstitial pneumonia
- Pulmonary fibrosis
- Diarrhea
Related conditions
Frequently asked questions
What drug class is melphalan?
melphalan belongs to: Oncology.
How does melphalan work?
Mechorethamine derivative that inhibits DNA & RNA synthesis via formation of carbonium ions; cross links DNA strands (interstrand and intrastrand crosslinking) causing miscoding breakage and subsequently DNA replication failure
What are the common side effects of melphalan?
Vomiting, Nausea, Myelosuppression, Stomatitis, Interstitial pneumonia, Pulmonary fibrosis, Diarrhea
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