Drug reference

peginterferon alfa 2b

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Anti Virals (Hepatits Viruses)

Mechanism of action

Immunomodulatory cytokine that enhances phagocytic activity of macrophages and cytotoxic activity of lymphocytes for target cells

Common side effects

  • Alopecia
  • Insomnia
  • Headache
  • Fatigue
  • Nausea
  • Depression
  • Injection site inflammation/reaction

Contraindications

  • Hypersensitivity Autoimmune hepatitis Decompensated liver disease (Child-Pugh >6 [class B and C])
  • Contraindications for combination therapy with ribavirin: Pregnant women and men whose female partners are pregnant Hemoglobinopathies (e.g., thalassemia major, sickle-cell anemia) Creatinine clearance less than 50 mL/min

Related conditions

Frequently asked questions

What drug class is peginterferon alfa 2b?

peginterferon alfa 2b belongs to: Anti Virals.

How does peginterferon alfa 2b work?

Immunomodulatory cytokine that enhances phagocytic activity of macrophages and cytotoxic activity of lymphocytes for target cells

What are the common side effects of peginterferon alfa 2b?

Alopecia, Insomnia, Headache, Fatigue, Nausea, Depression, Injection site inflammation/reaction

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