Drug reference
pregabalin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Anti Epileptic Drugs)
Mechanism of action
Precise mechanism of action unknown but is a GABA analogue that binds to a subunit of voltage-gated calcium channels in CNS; does not affect sodium channels, opiate receptors, or cyclo-oxygenase enzyme activity
Common side effects
- Dizziness
- Somnolence
- Fatigue
- Xerostomia
- Ataxia
- Peripheral edema
Known interactions (3)
- ethanol (alcohol) + pregabalin Moderate
- Gabapentin + pregabalin Moderate
- Mirogabalin + pregabalin Moderate
Related conditions
Frequently asked questions
What drug class is pregabalin?
pregabalin belongs to: Central Nervous System.
How does pregabalin work?
Precise mechanism of action unknown but is a GABA analogue that binds to a subunit of voltage-gated calcium channels in CNS; does not affect sodium channels, opiate receptors, or cyclo-oxygenase enzyme activity
What are the common side effects of pregabalin?
Dizziness, Somnolence, Fatigue, Xerostomia, Ataxia, Peripheral edema
Which drugs interact with pregabalin?
ethanol (alcohol), Gabapentin, Mirogabalin
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