Drug reference
varenicline
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Respiratory (Nicotinic agonist)
Mechanism of action
Agonist at nicotinic receptors; acts on mesolimbic dopamine system associated with nicotine addiction, where it prevents nicotine stimulation; stimulates nicotine activity but to lesser degree than nicotine does.
Common side effects
- Insomnia
- Headache
- Nausea
- Abnormal dreams
Contraindications
- Documented hypersensitivity or skin reactions to drug or components of formulation Nonsmokers
Related conditions
Frequently asked questions
What drug class is varenicline?
varenicline belongs to: Respiratory.
How does varenicline work?
Agonist at nicotinic receptors; acts on mesolimbic dopamine system associated with nicotine addiction, where it prevents nicotine stimulation; stimulates nicotine activity but to lesser degree than nicotine does.
What are the common side effects of varenicline?
Insomnia, Headache, Nausea, Abnormal dreams
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