Drug interactions
Amlodipine + Calcium acetate
Severity: Minor
Amlodipine and Calcium acetate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium salts can partly antagonize calcium channel blockers, mainly when given intravenously. Oral calcium acetate as a phosphate binder rarely has a meaningful effect on amlodipine's blood pressure lowering.
What this interaction means in plain words
Amlodipine and Calcium acetate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine belongs to Cardiovascular; Calcium acetate belongs to Genitourinary.
Why it happens
Elevated serum calcium may pharmacodynamically oppose calcium channel blockade.
What to do
No dose change is routinely needed; monitor blood pressure and serum calcium in patients on calcium acetate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine
- Amifostine + Amlodipine Major
- Amlodipine + Ombitasvir / paritaprevir / ritonavir and dasabuvir Major
- Activated Charcoal + Amlodipine Moderate
- Aldesleukin + Amlodipine Moderate
- Alfuzosin + Amlodipine Moderate
- Amlodipine + Apalutamide Moderate
Other interactions of Calcium acetate
Frequently asked questions
Can I take Amlodipine with Calcium acetate?
MediHelp rates the interaction as minor. Amlodipine and Calcium acetate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium salts can partly antagonize calcium channel blockers, mainly when given intravenously. Oral calcium acetate as a phosphate binder rarely has a meaningful effect on amlodipine's blood pressure lowering.
How serious is the interaction between Amlodipine and Calcium acetate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is routinely needed; monitor blood pressure and serum calcium in patients on calcium acetate.
What other medicines interact with Amlodipine?
MediHelp also lists interactions of Amlodipine with, for example, Amifostine, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Activated Charcoal. The full list is on the Amlodipine page.
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