Drug interactions
Amlodipine + Dapagliflozin-metformin
Severity: Minor
Amlodipine and Dapagliflozin-metformin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium channel blockers may slightly impair glucose tolerance in some patients, but clinically relevant loss of glycemic control with amlodipine is uncommon.
What this interaction means in plain words
Amlodipine and Dapagliflozin-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine belongs to Cardiovascular; Dapagliflozin-metformin belongs to Endocrine.
Why it happens
Possible small reduction in insulin secretion or sensitivity; mechanism not firmly established.
What to do
No routine adjustment needed. Monitor blood glucose as part of usual diabetes care.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dapagliflozin-metformin
Other interactions of Amlodipine
- Amifostine + Amlodipine Major
- Amlodipine + Ombitasvir / paritaprevir / ritonavir and dasabuvir Major
- Activated Charcoal + Amlodipine Moderate
- Aldesleukin + Amlodipine Moderate
- Alfuzosin + Amlodipine Moderate
- Amlodipine + Apalutamide Moderate
Frequently asked questions
Can I take Amlodipine with Dapagliflozin-metformin?
MediHelp rates the interaction as minor. Amlodipine and Dapagliflozin-metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium channel blockers may slightly impair glucose tolerance in some patients, but clinically relevant loss of glycemic control with amlodipine is uncommon.
How serious is the interaction between Amlodipine and Dapagliflozin-metformin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment needed. Monitor blood glucose as part of usual diabetes care.
What other medicines interact with Dapagliflozin-metformin?
MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Dapagliflozin-metformin page.
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