Drug interactions
Amlodipine + Nadolol
Severity: Minor
Amlodipine and Nadolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Amlodipine and nadolol are frequently combined for hypertension or angina, and the combination is generally well tolerated. Additive blood pressure lowering can occur, and beta-blockade may rarely worsen heart failure or bradycardia in susceptible patients.
What this interaction means in plain words
Amlodipine and Nadolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine belongs to Cardiovascular; Nadolol belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic effects of calcium channel blockade and beta-adrenergic blockade.
What to do
Monitor blood pressure and heart rate when starting or adjusting the combination, especially in patients with heart failure or conduction disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine
- Amifostine + Amlodipine Major
- Amlodipine + Ombitasvir / paritaprevir / ritonavir and dasabuvir Major
- Activated Charcoal + Amlodipine Moderate
- Aldesleukin + Amlodipine Moderate
- Alfuzosin + Amlodipine Moderate
- Amlodipine + Apalutamide Moderate
Other interactions of Nadolol
Frequently asked questions
Can I take Amlodipine with Nadolol?
MediHelp rates the interaction as minor. Amlodipine and Nadolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Amlodipine and nadolol are frequently combined for hypertension or angina, and the combination is generally well tolerated. Additive blood pressure lowering can occur, and beta-blockade may rarely worsen heart failure or bradycardia in susceptible patients.
How serious is the interaction between Amlodipine and Nadolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or adjusting the combination, especially in patients with heart failure or conduction disease.
What other medicines interact with Amlodipine?
MediHelp also lists interactions of Amlodipine with, for example, Amifostine, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Activated Charcoal. The full list is on the Amlodipine page.
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