Drug interactions
Amlodipine-atorvastatin + Magnesium supplement
Severity: Minor
Amlodipine-atorvastatin and Magnesium supplement: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Magnesium has calcium-antagonist and vasodilatory properties, which may add to the blood pressure lowering of amlodipine. Parenteral magnesium with calcium channel blockers has been associated with hypotension and neuromuscular weakness. Oral supplements pose less risk.
What this interaction means in plain words
Amlodipine-atorvastatin and Magnesium supplement have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive calcium antagonism and vasodilation.
What to do
Monitor blood pressure when giving intravenous magnesium. No routine change is needed for oral supplements.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-atorvastatin
Frequently asked questions
Can I take Amlodipine-atorvastatin with Magnesium supplement?
MediHelp rates the interaction as minor. Amlodipine-atorvastatin and Magnesium supplement have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Magnesium has calcium-antagonist and vasodilatory properties, which may add to the blood pressure lowering of amlodipine. Parenteral magnesium with calcium channel blockers has been associated with hypotension and neuromuscular weakness. Oral supplements pose less risk.
How serious is the interaction between Amlodipine-atorvastatin and Magnesium supplement?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure when giving intravenous magnesium. No routine change is needed for oral supplements.
What other medicines interact with Amlodipine-atorvastatin?
MediHelp also lists interactions of Amlodipine-atorvastatin with, for example, Amifostine, Apalutamide, Atazanavir. The full list is on the Amlodipine-atorvastatin page.
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