Drug reference
amlodipine-atorvastatin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Combination(CVS))
Mechanism of action
Amlodipine: CCB: inhibits extracellular Ca ions across the membranes of myocardial cells and vascular smooth muscle cells, without changing serum calcium concentrations. Atorvastatin: HMG-CoA reductase inhibitor, inhibits rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase
Common side effects
- Arthralgia
- Palpitation
- Nasopharingitis
- Diarrhea
- Peripheral edema
Contraindications
- Hypersensitivity to amlodipine or atorvastatin Active liver disease, or unexplained elevated transminases
Known interactions (1)
- amlodipine-atorvastatin + dantrolene Moderate
Related conditions
Frequently asked questions
What drug class is amlodipine-atorvastatin?
amlodipine-atorvastatin belongs to: Cardiovascular.
How does amlodipine-atorvastatin work?
Amlodipine: CCB: inhibits extracellular Ca ions across the membranes of myocardial cells and vascular smooth muscle cells, without changing serum calcium concentrations. Atorvastatin: HMG-CoA reductase inhibitor, inhibits rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase
What are the common side effects of amlodipine-atorvastatin?
Arthralgia, Palpitation, Nasopharingitis, Diarrhea, Peripheral edema
Which drugs interact with amlodipine-atorvastatin?
dantrolene
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