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Drug interactions

Amlodipine-benazepril + Bromocriptine

Severity: Moderate

Amlodipine-benazepril and Bromocriptine: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Bromocriptine can cause orthostatic hypotension, especially at initiation, and this adds to the effect of amlodipine and benazepril. Syncope and dizziness may occur.

What this interaction means in plain words

Amlodipine-benazepril and Bromocriptine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Amlodipine-benazepril belongs to Cardiovascular; Bromocriptine belongs to Central Nervous System.

Evidence level: Low

Why it happens

Additive hypotension from dopamine agonism and antihypertensive drug effects.

What to do

Start bromocriptine at a low dose and titrate slowly. Monitor blood pressure and consider lowering antihypertensive doses if hypotension occurs.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Amlodipine-benazepril with Bromocriptine?

MediHelp rates the interaction as moderate. Amlodipine-benazepril and Bromocriptine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bromocriptine can cause orthostatic hypotension, especially at initiation, and this adds to the effect of amlodipine and benazepril. Syncope and dizziness may occur.

How serious is the interaction between Amlodipine-benazepril and Bromocriptine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Start bromocriptine at a low dose and titrate slowly. Monitor blood pressure and consider lowering antihypertensive doses if hypotension occurs.

What other medicines interact with Amlodipine-benazepril?

MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.

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