Drug interactions
Amlodipine-benazepril + Calcium carbonate
Severity: Minor
Amlodipine-benazepril and Calcium carbonate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antacids containing calcium may slightly reduce the absorption of some ACE inhibitors, but the effect on benazepril is small and of uncertain clinical significance. Blood pressure control is rarely affected.
What this interaction means in plain words
Amlodipine-benazepril and Calcium carbonate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-benazepril belongs to Cardiovascular; Calcium carbonate belongs to Gastrointestinal Tract.
Why it happens
Possible reduced gastrointestinal absorption of the ACE inhibitor; mechanism not firmly established.
What to do
Separate doses by about 2 hours if convenient. Monitor blood pressure if antacids are used regularly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Other interactions of Calcium carbonate
Frequently asked questions
Can I take Amlodipine-benazepril with Calcium carbonate?
MediHelp rates the interaction as minor. Amlodipine-benazepril and Calcium carbonate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antacids containing calcium may slightly reduce the absorption of some ACE inhibitors, but the effect on benazepril is small and of uncertain clinical significance. Blood pressure control is rarely affected.
How serious is the interaction between Amlodipine-benazepril and Calcium carbonate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by about 2 hours if convenient. Monitor blood pressure if antacids are used regularly.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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