Drug interactions
Amlodipine-benazepril + Dalteparin
Severity: Moderate
Amlodipine-benazepril and Dalteparin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Heparins, including low molecular weight heparins, can suppress aldosterone production. Combined with an ACE inhibitor such as benazepril, this can raise serum potassium, especially in patients with renal impairment or diabetes.
What this interaction means in plain words
Amlodipine-benazepril and Dalteparin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-benazepril belongs to Cardiovascular; Dalteparin belongs to Cardiovascular.
Why it happens
Heparin-induced suppression of adrenal aldosterone synthesis adds to the potassium-retaining effect of ACE inhibition.
What to do
Monitor serum potassium and renal function when anticoagulation is prolonged, particularly in patients with kidney disease or diabetes. Review other potassium-raising agents.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-benazepril
- Aliskiren + Amlodipine-benazepril Contraindicated
- Amlodipine-benazepril + Sacubitril / valsartan Contraindicated
- Aldesleukin + Amlodipine-benazepril Major
- Amifostine + Amlodipine-benazepril Major
- Amiloride + Amlodipine-benazepril Major
- Amlodipine-benazepril + Azilsartan Major
Other interactions of Dalteparin
- Dalteparin + Defibrotide Contraindicated
- Dalteparin + Ketorolac Contraindicated
- Dalteparin + Mifepristone Contraindicated
- Abciximab + Dalteparin Major
- Acalabrutinib + Dalteparin Major
- Aceclofenac + Dalteparin Major
Frequently asked questions
Can I take Amlodipine-benazepril with Dalteparin?
MediHelp rates the interaction as moderate. Amlodipine-benazepril and Dalteparin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Heparins, including low molecular weight heparins, can suppress aldosterone production. Combined with an ACE inhibitor such as benazepril, this can raise serum potassium, especially in patients with renal impairment or diabetes.
How serious is the interaction between Amlodipine-benazepril and Dalteparin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and renal function when anticoagulation is prolonged, particularly in patients with kidney disease or diabetes. Review other potassium-raising agents.
What other medicines interact with Amlodipine-benazepril?
MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.
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