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Drug interactions

Amlodipine-benazepril + Mirabegron

Severity: Minor

Amlodipine-benazepril and Mirabegron: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Mirabegron can raise blood pressure in some patients, which may offset the effect of antihypertensives. The effect is usually modest.

What this interaction means in plain words

Amlodipine-benazepril and Mirabegron have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Amlodipine-benazepril belongs to Cardiovascular; Mirabegron belongs to Genitourinary.

Evidence level: Low

Why it happens

Pharmacodynamic opposition from the pressor effect of beta-3 agonism.

What to do

Check blood pressure before and during mirabegron treatment and adjust antihypertensive therapy if control worsens.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Amlodipine-benazepril with Mirabegron?

MediHelp rates the interaction as minor. Amlodipine-benazepril and Mirabegron have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Mirabegron can raise blood pressure in some patients, which may offset the effect of antihypertensives. The effect is usually modest.

How serious is the interaction between Amlodipine-benazepril and Mirabegron?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check blood pressure before and during mirabegron treatment and adjust antihypertensive therapy if control worsens.

What other medicines interact with Amlodipine-benazepril?

MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.

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