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Drug interactions

Amlodipine-benazepril + Nabilone

Severity: Minor

Amlodipine-benazepril and Nabilone: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Nabilone can cause orthostatic hypotension and tachycardia. Combined with an ACE inhibitor and a calcium channel blocker, blood pressure lowering may be increased, with dizziness or fainting.

What this interaction means in plain words

Amlodipine-benazepril and Nabilone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Amlodipine-benazepril belongs to Cardiovascular; Nabilone belongs to Gastrointestinal Tract.

Evidence level: Low

Why it happens

Additive pharmacodynamic hypotensive effects; nabilone has cannabinoid-mediated vasodilatory and autonomic effects.

What to do

Monitor blood pressure and orthostatic symptoms when nabilone is started or the dose is changed. Advise slow position changes.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Amlodipine-benazepril with Nabilone?

MediHelp rates the interaction as minor. Amlodipine-benazepril and Nabilone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nabilone can cause orthostatic hypotension and tachycardia. Combined with an ACE inhibitor and a calcium channel blocker, blood pressure lowering may be increased, with dizziness or fainting.

How serious is the interaction between Amlodipine-benazepril and Nabilone?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and orthostatic symptoms when nabilone is started or the dose is changed. Advise slow position changes.

What other medicines interact with Amlodipine-benazepril?

MediHelp also lists interactions of Amlodipine-benazepril with, for example, Aliskiren, Sacubitril / valsartan, Aldesleukin. The full list is on the Amlodipine-benazepril page.

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