Drug interactions
Amlodipine-olmesartan + Armodafinil
Severity: Minor
Amlodipine-olmesartan and Armodafinil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Armodafinil is a weak CYP3A4 inducer and may slightly reduce amlodipine concentrations. Armodafinil can also raise blood pressure, which may work against antihypertensive treatment.
What this interaction means in plain words
Amlodipine-olmesartan and Armodafinil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-olmesartan belongs to Cardiovascular; Armodafinil belongs to Central Nervous System.
Why it happens
Weak induction of CYP3A4 increases amlodipine clearance, and armodafinil has pressor effects.
What to do
Monitor blood pressure after starting or stopping armodafinil and adjust antihypertensive therapy if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-olmesartan
- Aliskiren + Amlodipine-olmesartan Contraindicated
- Amlodipine-olmesartan + Sparsentan Contraindicated
- Amifostine + Amlodipine-olmesartan Major
- Amiloride + Amlodipine-olmesartan Major
- Amlodipine-olmesartan + Benazepril Major
- Amlodipine-olmesartan + Captopril Major
Other interactions of Armodafinil
Frequently asked questions
Can I take Amlodipine-olmesartan with Armodafinil?
MediHelp rates the interaction as minor. Amlodipine-olmesartan and Armodafinil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Armodafinil is a weak CYP3A4 inducer and may slightly reduce amlodipine concentrations. Armodafinil can also raise blood pressure, which may work against antihypertensive treatment.
How serious is the interaction between Amlodipine-olmesartan and Armodafinil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure after starting or stopping armodafinil and adjust antihypertensive therapy if needed.
What other medicines interact with Amlodipine-olmesartan?
MediHelp also lists interactions of Amlodipine-olmesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Amlodipine-olmesartan page.
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