Drug interactions
Amlodipine-olmesartan-hydrochlorothiazide + Etrasimod
Severity: Minor
Amlodipine-olmesartan-hydrochlorothiazide and Etrasimod: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etrasimod can cause transient bradycardia and AV conduction delay on initiation. Amlodipine is a dihydropyridine without significant heart rate lowering effect, so a meaningful interaction is not expected.
What this interaction means in plain words
Amlodipine-olmesartan-hydrochlorothiazide and Etrasimod have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Etrasimod belongs to Gastrointestinal Tract.
Why it happens
Theoretical additive hemodynamic effects; amlodipine does not meaningfully slow heart rate or AV conduction.
What to do
No specific action beyond routine heart rate and blood pressure monitoring at etrasimod initiation.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-olmesartan-hydrochlorothiazide
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide Contraindicated
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide Contraindicated
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan Contraindicated
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide Major
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide Major
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide Major
Other interactions of Etrasimod
- Abatacept + Etrasimod Major
- Amiodarone + Etrasimod Major
- Anagrelide + Etrasimod Major
- Anakinra + Etrasimod Major
- Anti-thymocyte + Etrasimod Major
- Asenapine + Etrasimod Major
Frequently asked questions
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Etrasimod?
MediHelp rates the interaction as minor. Amlodipine-olmesartan-hydrochlorothiazide and Etrasimod have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Etrasimod can cause transient bradycardia and AV conduction delay on initiation. Amlodipine is a dihydropyridine without significant heart rate lowering effect, so a meaningful interaction is not expected.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Etrasimod?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action beyond routine heart rate and blood pressure monitoring at etrasimod initiation.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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