Drug interactions
Amlodipine-valsartan + Calcium gluconate
Severity: Minor
Amlodipine-valsartan and Calcium gluconate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Parenteral calcium gluconate can reverse calcium channel blocker effects and is used in overdose treatment. At usual oral supplement doses, the effect on amlodipine is small.
What this interaction means in plain words
Amlodipine-valsartan and Calcium gluconate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-valsartan belongs to Cardiovascular; Calcium gluconate belongs to Gastrointestinal Tract.
Why it happens
Increased extracellular calcium antagonizes L-type calcium channel blockade.
What to do
No action is needed for oral use; with intravenous calcium, monitor blood pressure and heart rate for a reduced amlodipine effect.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-valsartan
- Aliskiren + Amlodipine-valsartan Contraindicated
- Amlodipine-valsartan + Sparsentan Contraindicated
- Aldesleukin + Amlodipine-valsartan Major
- Amifostine + Amlodipine-valsartan Major
- Amiloride + Amlodipine-valsartan Major
- Amlodipine-valsartan + Benazepril Major
Other interactions of Calcium gluconate
- Calcium gluconate + Ceftriaxone Contraindicated
- Calcium gluconate + Digoxin Major
- Alendronate + Calcium gluconate Moderate
- Amlodipine-atorvastatin + Calcium gluconate Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Calcium gluconate Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Calcium gluconate Moderate
Frequently asked questions
Can I take Amlodipine-valsartan with Calcium gluconate?
MediHelp rates the interaction as minor. Amlodipine-valsartan and Calcium gluconate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Parenteral calcium gluconate can reverse calcium channel blocker effects and is used in overdose treatment. At usual oral supplement doses, the effect on amlodipine is small.
How serious is the interaction between Amlodipine-valsartan and Calcium gluconate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed for oral use; with intravenous calcium, monitor blood pressure and heart rate for a reduced amlodipine effect.
What other medicines interact with Amlodipine-valsartan?
MediHelp also lists interactions of Amlodipine-valsartan with, for example, Aliskiren, Sparsentan, Aldesleukin. The full list is on the Amlodipine-valsartan page.
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