Drug interactions
Amlodipine-valsartan + Dasatinib
Severity: Minor
Amlodipine-valsartan and Dasatinib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dasatinib is a weak CYP3A4 inhibitor and could slightly raise amlodipine levels. Dasatinib is also associated with fluid retention and edema, which may be confused with or add to amlodipine-related edema.
What this interaction means in plain words
Amlodipine-valsartan and Dasatinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-valsartan belongs to Cardiovascular; Dasatinib belongs to Oncology.
Why it happens
Weak inhibition of CYP3A4 may reduce amlodipine clearance.
What to do
Monitor blood pressure and peripheral edema, and adjust the amlodipine dose if symptoms develop.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-valsartan
- Aliskiren + Amlodipine-valsartan Contraindicated
- Amlodipine-valsartan + Sparsentan Contraindicated
- Aldesleukin + Amlodipine-valsartan Major
- Amifostine + Amlodipine-valsartan Major
- Amiloride + Amlodipine-valsartan Major
- Amlodipine-valsartan + Benazepril Major
Other interactions of Dasatinib
- Dasatinib + Saquinavir Contraindicated
- Dasatinib + Thioridazine Contraindicated
- Adagrasib + Dasatinib Major
- Amiodarone + Dasatinib Major
- Amisulpride + Dasatinib Major
- Amitriptyline + Dasatinib Major
Frequently asked questions
Can I take Amlodipine-valsartan with Dasatinib?
MediHelp rates the interaction as minor. Amlodipine-valsartan and Dasatinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dasatinib is a weak CYP3A4 inhibitor and could slightly raise amlodipine levels. Dasatinib is also associated with fluid retention and edema, which may be confused with or add to amlodipine-related edema.
How serious is the interaction between Amlodipine-valsartan and Dasatinib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and peripheral edema, and adjust the amlodipine dose if symptoms develop.
What other medicines interact with Amlodipine-valsartan?
MediHelp also lists interactions of Amlodipine-valsartan with, for example, Aliskiren, Sparsentan, Aldesleukin. The full list is on the Amlodipine-valsartan page.
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