Drug interactions
Amlodipine-valsartan + Liraglutide
Severity: Minor
Amlodipine-valsartan and Liraglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Valsartan may slightly improve insulin sensitivity and so add to the glucose lowering of liraglutide. Clinically significant hypoglycemia is unlikely with liraglutide alone but is more plausible if a sulfonylurea or insulin is also used.
What this interaction means in plain words
Amlodipine-valsartan and Liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-valsartan belongs to Cardiovascular; Liraglutide belongs to Endocrine.
Why it happens
Angiotensin receptor blockade may improve insulin sensitivity, adding to the glucose lowering of GLP-1 receptor agonism.
What to do
Monitor blood glucose when starting or adjusting therapy, and reduce the dose of any concurrent insulin or sulfonylurea if glucose falls.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-valsartan
- Aliskiren + Amlodipine-valsartan Contraindicated
- Amlodipine-valsartan + Sparsentan Contraindicated
- Aldesleukin + Amlodipine-valsartan Major
- Amifostine + Amlodipine-valsartan Major
- Amiloride + Amlodipine-valsartan Major
- Amlodipine-valsartan + Benazepril Major
Other interactions of Liraglutide
Frequently asked questions
Can I take Amlodipine-valsartan with Liraglutide?
MediHelp rates the interaction as minor. Amlodipine-valsartan and Liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Valsartan may slightly improve insulin sensitivity and so add to the glucose lowering of liraglutide. Clinically significant hypoglycemia is unlikely with liraglutide alone but is more plausible if a sulfonylurea or insulin is also used.
How serious is the interaction between Amlodipine-valsartan and Liraglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or adjusting therapy, and reduce the dose of any concurrent insulin or sulfonylurea if glucose falls.
What other medicines interact with Amlodipine-valsartan?
MediHelp also lists interactions of Amlodipine-valsartan with, for example, Aliskiren, Sparsentan, Aldesleukin. The full list is on the Amlodipine-valsartan page.
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