Drug interactions
Amobarbital + Dimenhydrinate
Severity: Moderate
Amobarbital and Dimenhydrinate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Together these agents add to drowsiness and psychomotor impairment, which can affect driving and increase fall risk. Effects are greater with alcohol and in older adults.
What this interaction means in plain words
Amobarbital and Dimenhydrinate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amobarbital belongs to Central Nervous System; Dimenhydrinate belongs to Respiratory.
Why it happens
Additive CNS depression via GABAergic enhancement and H1 antagonism.
What to do
Counsel on avoiding driving and alcohol, and use the lowest effective doses. Consider a less sedating antiemetic.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amobarbital
- Amobarbital + Calcium / magnesium / potassium / sodium oxybates Contraindicated
- Amobarbital + Doravirine Contraindicated
- Amobarbital + Elbasvir / grazoprevir Contraindicated
- Amobarbital + Isavuconazonium Contraindicated
- Amobarbital + Isocarboxazid Contraindicated
- Amobarbital + Lonafarnib Contraindicated
Other interactions of Dimenhydrinate
Frequently asked questions
Can I take Amobarbital with Dimenhydrinate?
MediHelp rates the interaction as moderate. Amobarbital and Dimenhydrinate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Together these agents add to drowsiness and psychomotor impairment, which can affect driving and increase fall risk. Effects are greater with alcohol and in older adults.
How serious is the interaction between Amobarbital and Dimenhydrinate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on avoiding driving and alcohol, and use the lowest effective doses. Consider a less sedating antiemetic.
What other medicines interact with Amobarbital?
MediHelp also lists interactions of Amobarbital with, for example, Calcium / magnesium / potassium / sodium oxybates, Doravirine, Elbasvir / grazoprevir. The full list is on the Amobarbital page.
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