Drug interactions
Amoxicillin + Bazedoxifene / conjugated estrogens
Severity: Minor
Amoxicillin and Bazedoxifene / conjugated estrogens: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antibiotics have been theorized to reduce enterohepatic recycling of estrogens by altering gut flora. For amoxicillin, pharmacokinetic studies have not shown a consistent drop in estrogen levels. Clinical significance is considered minimal.
What this interaction means in plain words
Amoxicillin and Bazedoxifene / conjugated estrogens have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical disruption of gut flora that deconjugate estrogens, reducing enterohepatic recirculation.
What to do
No action is generally needed for this menopausal therapy. Report any unexpected bleeding.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amoxicillin
- Amoxicillin + Methotrexate Major
- Amoxicillin + Bcg vaccine live Moderate
- Amoxicillin + Cholera vaccine Moderate
- Amoxicillin + Eravacycline Moderate
- Amoxicillin + Microbiota Moderate
- Amoxicillin + Mycophenolate Moderate
Frequently asked questions
Can I take Amoxicillin with Bazedoxifene / conjugated estrogens?
MediHelp rates the interaction as minor. Amoxicillin and Bazedoxifene / conjugated estrogens have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antibiotics have been theorized to reduce enterohepatic recycling of estrogens by altering gut flora. For amoxicillin, pharmacokinetic studies have not shown a consistent drop in estrogen levels. Clinical significance is considered minimal.
How serious is the interaction between Amoxicillin and Bazedoxifene / conjugated estrogens?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is generally needed for this menopausal therapy. Report any unexpected bleeding.
What other medicines interact with Amoxicillin?
MediHelp also lists interactions of Amoxicillin with, for example, Methotrexate, Bcg vaccine live, Cholera vaccine. The full list is on the Amoxicillin page.
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