Drug interactions
Amphotericin b deoxycholate + Mometasone
Severity: Minor
Amphotericin b deoxycholate and Mometasone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Systemic corticosteroids and amphotericin B both cause potassium loss, and combined use can cause marked hypokalemia. With inhaled mometasone, systemic exposure is low so the effect is likely small, but it may matter at high doses or in patients with other risk factors.
What this interaction means in plain words
Amphotericin b deoxycholate and Mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive renal potassium wasting from corticosteroid mineralocorticoid activity and amphotericin B tubular toxicity.
What to do
Monitor serum potassium and magnesium during amphotericin B therapy and replace as needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Amphotericin b deoxycholate and Mometasone, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Mometasone
- Mometasone + Ritonavir Major
- Atazanavir + Mometasone Moderate
- Clarithromycin + Mometasone Moderate
- Cobicistat + Mometasone Moderate
- Darunavir + Mometasone Moderate
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Mometasone Moderate
Frequently asked questions
Can I take Amphotericin b deoxycholate with Mometasone?
MediHelp rates the interaction as minor. Amphotericin b deoxycholate and Mometasone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Systemic corticosteroids and amphotericin B both cause potassium loss, and combined use can cause marked hypokalemia. With inhaled mometasone, systemic exposure is low so the effect is likely small, but it may matter at high doses or in patients with other risk factors.
How serious is the interaction between Amphotericin b deoxycholate and Mometasone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and magnesium during amphotericin B therapy and replace as needed.
What other medicines interact with Mometasone?
MediHelp also lists interactions of Mometasone with, for example, Ritonavir, Atazanavir, Clarithromycin. The full list is on the Mometasone page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
