Drug interactions
Ampicillin + Dexlansoprazole
Severity: Minor
Ampicillin and Dexlansoprazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Acid suppression may reduce oral ampicillin absorption, possibly lowering antibiotic exposure. The effect is generally small and its clinical relevance is uncertain.
What this interaction means in plain words
Ampicillin and Dexlansoprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ampicillin belongs to Anti Bacterial; Dexlansoprazole belongs to Gastrointestinal Tract.
Why it happens
Elevated gastric pH may alter the dissolution and absorption of oral ampicillin.
What to do
No routine change is needed; if an infection responds poorly, consider the interaction and review the dose or route.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dexlansoprazole
- Dexlansoprazole + Mavacamten Contraindicated
- Dexlansoprazole + Rilpivirine Contraindicated
- Acalabrutinib + Dexlansoprazole Major
- Atazanavir + Dexlansoprazole Major
- Dacomitinib + Dexlansoprazole Major
- Dasatinib + Dexlansoprazole Major
Other interactions of Ampicillin
- Allopurinol + Ampicillin Moderate
- Ampicillin + Bcg vaccine live Moderate
- Ampicillin + Chloramphenicol Moderate
- Ampicillin + Chloroquine Moderate
- Ampicillin + Cholera vaccine Moderate
- Ampicillin + Demeclocycline Moderate
Frequently asked questions
Can I take Ampicillin with Dexlansoprazole?
MediHelp rates the interaction as minor. Ampicillin and Dexlansoprazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Acid suppression may reduce oral ampicillin absorption, possibly lowering antibiotic exposure. The effect is generally small and its clinical relevance is uncertain.
How serious is the interaction between Ampicillin and Dexlansoprazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; if an infection responds poorly, consider the interaction and review the dose or route.
What other medicines interact with Dexlansoprazole?
MediHelp also lists interactions of Dexlansoprazole with, for example, Mavacamten, Rilpivirine, Acalabrutinib. The full list is on the Dexlansoprazole page.
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