Drug interactions
Ampicillin + Sarecycline
Severity: Minor
Ampicillin and Sarecycline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tetracyclines are bacteriostatic and may theoretically reduce the bactericidal effect of ampicillin. Sarecycline is used for acne with limited systemic exposure, so the clinical relevance is likely small.
What this interaction means in plain words
Ampicillin and Sarecycline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ampicillin belongs to Anti Bacterial; Sarecycline belongs to Anti Bacterial.
Why it happens
Bacteriostatic inhibition of protein synthesis may reduce the activity of beta-lactams that require bacterial cell growth.
What to do
No routine action is needed; monitor response to ampicillin if treating a serious infection.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ampicillin
- Allopurinol + Ampicillin Moderate
- Ampicillin + Bcg vaccine live Moderate
- Ampicillin + Chloramphenicol Moderate
- Ampicillin + Chloroquine Moderate
- Ampicillin + Cholera vaccine Moderate
- Ampicillin + Demeclocycline Moderate
Other interactions of Sarecycline
- Acitretin + Sarecycline Contraindicated
- Isotretinoin + Sarecycline Major
- Sarecycline + Tretinoin Major
- Aluminum hydroxide + Sarecycline Moderate
- Calcium carbonate + Sarecycline Moderate
- Calcium + Sarecycline Moderate
Frequently asked questions
Can I take Ampicillin with Sarecycline?
MediHelp rates the interaction as minor. Ampicillin and Sarecycline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tetracyclines are bacteriostatic and may theoretically reduce the bactericidal effect of ampicillin. Sarecycline is used for acne with limited systemic exposure, so the clinical relevance is likely small.
How serious is the interaction between Ampicillin and Sarecycline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; monitor response to ampicillin if treating a serious infection.
What other medicines interact with Ampicillin?
MediHelp also lists interactions of Ampicillin with, for example, Allopurinol, Bcg vaccine live, Chloramphenicol. The full list is on the Ampicillin page.
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