Drug interactions
Anagrelide + Fostemsavir
Severity: Moderate
Anagrelide and Fostemsavir: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anagrelide can prolong QTc, and fostemsavir has caused QTc prolongation at supratherapeutic doses. Combination may increase the risk of arrhythmia in patients with other risk factors.
What this interaction means in plain words
Anagrelide and Fostemsavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Anagrelide belongs to Cardiovascular; Fostemsavir belongs to Anti Virals.
Why it happens
Additive QT prolongation.
What to do
Obtain a baseline ECG and correct electrolyte abnormalities. Monitor the QTc in those with heart disease or other QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Anagrelide
- Anagrelide + Panobinostat Contraindicated
- Anagrelide + Pimozide Contraindicated
- Anagrelide + Thioridazine Contraindicated
- Anagrelide + Vandetanib Contraindicated
- Abrocitinib + Anagrelide Major
- Alfuzosin + Anagrelide Major
Other interactions of Fostemsavir
- Apalutamide + Fostemsavir Contraindicated
- Carbamazepine + Fostemsavir Contraindicated
- Enzalutamide + Fostemsavir Contraindicated
- Fostemsavir + Mitotane Contraindicated
- Fostemsavir + Phenytoin Contraindicated
- Fostemsavir + Rifampicin Contraindicated
Frequently asked questions
Can I take Anagrelide with Fostemsavir?
MediHelp rates the interaction as moderate. Anagrelide and Fostemsavir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anagrelide can prolong QTc, and fostemsavir has caused QTc prolongation at supratherapeutic doses. Combination may increase the risk of arrhythmia in patients with other risk factors.
How serious is the interaction between Anagrelide and Fostemsavir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and correct electrolyte abnormalities. Monitor the QTc in those with heart disease or other QT-prolonging drugs.
What other medicines interact with Anagrelide?
MediHelp also lists interactions of Anagrelide with, for example, Panobinostat, Pimozide, Thioridazine. The full list is on the Anagrelide page.
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