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Drug interactions

Arformoterol + Hydroxychloroquine

Severity: Moderate

Arformoterol and Hydroxychloroquine: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Hydroxychloroquine prolongs the QT interval and long-acting beta-agonists such as arformoterol may add to this effect and lower potassium. The combination can increase arrhythmia risk, especially in patients with cardiac disease.

What this interaction means in plain words

Arformoterol and Hydroxychloroquine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Arformoterol belongs to Respiratory; Hydroxychloroquine belongs to Musculoskeletal.

Evidence level: Low

Why it happens

Additive QT prolongation, with beta-2 agonist-induced hypokalemia and tachycardia.

What to do

Monitor ECG in patients with cardiac disease or other QT risk factors and check potassium when clinically indicated.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Arformoterol with Hydroxychloroquine?

MediHelp rates the interaction as moderate. Arformoterol and Hydroxychloroquine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hydroxychloroquine prolongs the QT interval and long-acting beta-agonists such as arformoterol may add to this effect and lower potassium. The combination can increase arrhythmia risk, especially in patients with cardiac disease.

How serious is the interaction between Arformoterol and Hydroxychloroquine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG in patients with cardiac disease or other QT risk factors and check potassium when clinically indicated.

What other medicines interact with Hydroxychloroquine?

MediHelp also lists interactions of Hydroxychloroquine with, for example, Arsenic trioxide, Cisapride, Dronedarone. The full list is on the Hydroxychloroquine page.

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