Drug reference

hydroxychloroquine

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Musculoskeletal (DMARDs)

Mechanism of action

Mechanisms underlying the anti-inflammatory and immunomodulatory effects of hydroxychloroquine are unknown. Hydroxychloroquine, like chloroquine, is a weak base and may exert its effect by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. It can also inhibit certain enzymes by its interaction with DNA.

Common side effects

  • Anemia
  • Fatigue
  • Nausea
  • Thrombocytopenia
  • Vertigo
  • Nerve deafness

Contraindications

  • Hypersensitivity to 4-aminoquinoline derivatives

Known interactions (5)

Related conditions

Frequently asked questions

What drug class is hydroxychloroquine?

hydroxychloroquine belongs to: Musculoskeletal.

How does hydroxychloroquine work?

Mechanisms underlying the anti-inflammatory and immunomodulatory effects of hydroxychloroquine are unknown. Hydroxychloroquine, like chloroquine, is a weak base and may exert its effect by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. It can also inhibit certain enzymes by its interaction with DNA.

What are the common side effects of hydroxychloroquine?

Anemia, Fatigue, Nausea, Thrombocytopenia, Vertigo, Nerve deafness

Which drugs interact with hydroxychloroquine?

azithromycin, levofloxacin, loperamide, hepatitis a vaccine inactivated, pneumococcal vaccine 13-valent

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