Skip to content

Drug interactions

Arformoterol + Trazodone

Severity: Minor

Arformoterol and Trazodone: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Tricyclic antidepressants can potentiate the cardiovascular effects of long-acting beta-agonists, but trazodone is not a tricyclic. Both drugs can affect QT and heart rate, so any interaction is likely to be small.

What this interaction means in plain words

Arformoterol and Trazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Arformoterol belongs to Respiratory; Trazodone belongs to Central Nervous System.

Evidence level: Low

Why it happens

Possible minor additive effects on QT interval and heart rate; not well established for trazodone.

What to do

No routine adjustment is needed. Monitor ECG in patients with cardiac disease or hypokalemia.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ members

Unlock the full page

Create an account and start a Pro+ trial to unlock the full management advice for Arformoterol and Trazodone, the additional notes, the evidence detail and the whole-prescription interaction checker.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Try Pro+ free for 7 days on the web. No card needed.

Frequently asked questions

Can I take Arformoterol with Trazodone?

MediHelp rates the interaction as minor. Arformoterol and Trazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tricyclic antidepressants can potentiate the cardiovascular effects of long-acting beta-agonists, but trazodone is not a tricyclic. Both drugs can affect QT and heart rate, so any interaction is likely to be small.

How serious is the interaction between Arformoterol and Trazodone?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Monitor ECG in patients with cardiac disease or hypokalemia.

What other medicines interact with Trazodone?

MediHelp also lists interactions of Trazodone with, for example, Arsenic trioxide, Ibutilide, Isocarboxazid. The full list is on the Trazodone page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug interactions

Get the app Sign in